Abstract: In this paper, existing forms of arsenic in the seafood that are connected with food safety and seashells physiology and biochemistry was reviewed. The limit content of arsenic in seawater is no more than 0.03mg/kg based on the standards, while, inorganic arsenic in soft tissue of seashell is between 0.Smg/kg and lmg/kg. At present, two-compartment model was applied to describe the heavy metal harm on shells. The other models was changed or improve from two-compartment model. It is proposed to strengthen the hazards of heavy metals on the description ofAnadara uropygimelana. This work responds to international technical barriers to trade actively, and also expands the area of heavy metals in shellfish.

Key words: arsenic, food safety, standards, seashell